Our digestive system performs a big job. It takes in water, food, and bacteria from outside and converts them into nutrients to repair, grow and maintain the body. Serotonin is a monoamine neurotransmitter that helps to regulate sleep, mood, and learning and impact the self-esteem and happiness of the person. A major amount of serotonin is present in our gut. It helps to secrete some enzymes for the digestion of food. Gut to brain signals affects memory, learning and ability to take decisions and directly affect the feeling of stress or sadness. Similarly and emotions of the brain also affect the digestive tract.

The connection between brain and digestive system:

  • Whatever goes in your stomach can change your mood
  • Stress causes the gut to brain cravings
  • Diet affects the gut bacteria and gut bacteria affects the brain

A thought of eating in mind can release the stomach juices before you eat the food. So obviously digestive health influence the functions of brain and brain health also affect the function of digestive system. Digestive system and brain both are closely connected to each other. A disturbed brain transfers signals to the gut and a disturbed gut transfers signals to the brain. Stomach affliction can be caused by stress, anxiety or depression.

Gut sends signals and chemicals directly to the brain. Communication signals from gut viscera to brain involve around 90% of nerve signals. Primary issues that impact this gut-brain relationship are parasites, antibiotics or factors causing leaky gut syndrome. Commonly prescribed antibiotics forbid the growth of various types of good bacteria in the gut. Deficiency of these bacteria can potentially result in some brain conditions like autism. Sometimes the parasitic toxins may travel from stomach to brain and can cause severe damage to the brain. Stress increases the penetrability of the intestine and causes a leaky gut, as a result bacteria are allowed to cross blood barrier that causes organ damage and also affects surrounding areas.

The digestive tract is also designated as the second brain by some experts because it is very sensitive to emotions. Plenty of bacteria lies in digestive system called as a micro biome. These bacteria execute many functions including food breakdown and fight against Infections. Studies reveal that low levels of Bacteroides i.e. a common gut bacterium may cause anxiety, stress and autism. A Micro biome, which is an intestinal organism, participate in a variety of systems of the body including detoxification, immunity, inflammation, vitamin production, neurotransmitter, nutrient absorption, feeling of full or hungry, utilization of fats and carbohydrates. The Micro biome also has an effect on mood, libido, and clarity of thoughts and understanding of the world. Micro biome dysfunction can cause headaches, poor concentration, anxiety and even an adverse perspective on life.


Brain and stomach have a direct connection. Both affect each other. Brain function is directed by working of the gut. Intestinal activities affect daily functions of the brain and also conclude the risk of many neurological conditions. Central nervous system is most sensitive to gut bacteria changes than any other system of the body. Research shows that digestive health can effectively affect the mood and well-being of the person.